The Division of Sport Science at Incheon National University: Pioneering the Future of Sport Science

Research

Exercise Physiology & Biochemistry Lab

The Exercise Physiology & Biochemistry Laboratory conducts research on physiological responses to exercise in both animal and human models. The lab primarily focuses on the study of myokines induced by exercise, exploring their mechanisms through animal experiments. In addition, it aims to identify and implement the most effective types and intensities of exercise to enhance exerkine secretion in humans.

Ongoing research also investigates the role of exerkines in the interaction between skeletal muscle mass and cognitive function, with the goal of understanding how exercise-mediated molecular responses contribute to overall health and performance.

Academic Advisor Sewon Lee

032-835-8572

leesew@inu.ac.kr

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Lab Introduction

The Exercise Physiology & Biochemistry Laboratory conducts research on physiological responses to exercise in both animal and human models. The lab primarily focuses on the study of myokines induced by exercise, exploring their mechanisms through animal experiments. In addition, it aims to identify and implement the most effective types and intensities of exercise to enhance exerkine secretion in humans.

Ongoing research also investigates the role of exerkines in the interaction between skeletal muscle mass and cognitive function, with the goal of understanding how exercise-mediated molecular responses contribute to overall health and performance.

Main Research

  • Study on the Efficacy of Preventive Exercise and the Mechanism of Myokine-Mediated Vascular Function Improvement in Young Women with Normal-Weight Obesity
    (Basic Science Research Program – Mid-Career Researcher Support, 2022–2025)

  • Effects of Obesity and Single vs. Chronic Exercise on the PGC1α–FNDC5/Irisin–UCP1 Signaling Pathway
    (Basic Science Research Program – General Research, 2019–2022)

  • Mechanisms of Downregulation in Vascular Kv7 Channel Activation in Type 2 Diabetes Mellitus
    (Basic Science Research Program – Young Investigator Grant, 2017–2019)

  • Experimental Data Collection for Activity Estimation Using Smart Bands
    (University–Industry Cooperative Research, 2020–2021)

  • Correlation Between Skeletal Muscle Mass and Metabolic/Cardiovascular Risk Factors in Healthy Young Adults
    (Korean Society for the Study of Obesity, 2019–2020)

Main Research Areas
skeletal muscle mass exerkine normal weight obesity cognitive function vascular function
Research Projects
  • Effects of Obesity and Single vs. Chronic Exercise on the PGC1α–FNDC5/Irisin–UCP1 Signaling Pathway
  • Experimental Data Collection for Activity Estimation Using Smart Bands
  • Efficacy of Preventive Exercise and Mechanisms of Myokine-Mediated Vascular Function Improvement in Young Women with Normal-Weight Obesity
  • Effects of Exercise Type and Intensity on Myokines and Appetite-Regulating Hormones in Women with Normal-Weight Obesity
Publication
  • Cho C, Ji M, Cho E, Yi S, Kim JG, Lee S. Chronic voluntary wheel running exercise ameliorates metabolic dysfunction via PGC-1α expression independently of FNDC5/irisin pathway in high fat diet-induced obese mice. The Journal of Physiological Sciences.
  • Cho C, Jeon K, Lee S. Body Composition Evaluation of Elementary School Students Using Bioelectrical Impedance Analysis in South Korea. Iranian Journal of Public Health.
  • Kim N, Lee S, Byun K. Effects of Limiting the Number of Ball Touches on Physical and Technical Performance of the Junior Football Players during Small-sided Game. Exercise Science.